[Ireland] PhD Studentship in Life Sciences and Medicine at University College Dublin
Project Title
Molecular characterisation of familial colorectal cancers.
Project Description
Colorectal cancer is the second leading cause of cancer related death in Ireland. This project will focus on the identification of molecular features that further discriminate between sporadic and familial subsets of colorectal cancer. This should lead to improved diagnosis and prognosis and also provide a basis for future molecular target-based intervention studies.
This Health Research Board of Ireland funded PhD project will be based in the Conway Institute of Biomolecular and Biomedical Research at University College Dublin. The study is part of an ongoing collaboration with the Centre for Colorectal Disease in St. Vincent`s University Hospital Dublin and will provide opportunities for interaction with the clinical research environment within that hospital.
Techniques will include array comparative genomic hybridisation (aCGH), mutation detection and methylation analysis. High throughput immunohistochemical analysis will be carried out using tissue microarray methodology using an automated microscopy imaging system with advanced image analysis software. This project has the potential to translate advances in molecular genetics into improved patient care.
Qualifications
Good honours degree or an MSc, in a biological science or related subject. Familiarity with basic techniques in molecular biology would be an advantage.
Application Deadline 16-Oct-06
University College Dublin
http://www.ucd.ie/conway/
School of Medicine and Medical Science
Dr. Dermot Leahy
dermot.leahy@ucd.ie
Dublin
Ireland
Filed under: Postgraduate
